Dividends paid (USD per share)
Common Stock, Dividends, Per Share, Cash Paid
Net unrealized gain on short-term investments
Unrealized Gain (Loss) on Investments
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Statistical Measurement
Statistical Measurement [Domain]
Adjusted Cost
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss
Award Timing Predetermined
Award Timing Predetermined [Flag]
2025 (remainder of the year)
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
Entity File Number
Entity File Number
Additional Paid-In Capital
Additional Paid-in Capital [Member]
Released (in shares)
Share-Based Compensation Arrangement By Share-Based Payment Award, Equity Instruments Other Than Options, Releases in Period
Share-Based Compensation Arrangement By Share-Based Payment Award, Equity Instruments Other Than Options, Releases in Period
Tabular List, Table
Tabular List [Table Text Block]
Leases [Abstract]
Leases [Abstract]
2020 Stock Options and Incentive Plan and 2022 Inducement Plan
Two Thousand And Twenty Stock Options And Incentive Plan And Two Thousand Twenty Two Inducement Plan [Member]
Two Thousand And Twenty Stock Options And Incentive Plan And Two Thousand Twenty Two Inducement Plan
Accounting Pronouncements Not Yet Adopted
New Accounting Pronouncements, Policy [Policy Text Block]
Purchase of short-term investments
Payments to Acquire Short-Term Investments
Accounts payable
Increase (Decrease) in Accounts Payable
Type of Restructuring [Domain]
Type of Restructuring [Domain]
Performance-Based Restricted Stock Units, TSR Goal
Performance-Based Restricted Stock Units, TSR Goal [Member]
Performance-Based Restricted Stock Units, TSR Goal
Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Trading Arrangements, by Individual
Trading Arrangements, by Individual [Table]
Net loss per share - basic (USD per share)
Earnings Per Share, Basic
Adjustment to Compensation:
Adjustment to Compensation [Axis]
Named Executive Officers, Footnote
Named Executive Officers, Footnote [Text Block]
Warrant, Acquiring Person's beneficial ownership threshold, non-passive investor
Class Of Warrant Or Right, Acquiring Person's Beneficial Ownership Threshold, Non-Passive Investor
Class Of Warrant Or Right, Acquiring Person's Beneficial Ownership Threshold, Non-Passive Investor
Total shares reserved for future issuance (in shares)
Common Stock, Capital Shares Reserved for Future Issuance
Interest and other income (expense), net
Interest and other (income) expense, net
Interest And Other Income (Expense), Net
Interest And Other Income (Expense), Net
Schedule of Stock by Class [Table]
Stock, Class of Stock [Table]
Schedule of Segment Reporting Expenses
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Shares of common stock available for future grants under the 2020 Stock Option and Incentive Plan
Two Thousand And Twenty Stock Options And Incentive Plan [Member]
2020 Stock options and incentive plan.
Prepaid licenses
Prepaid Licenses, Current
Prepaid Licenses, Current
Accrued Liabilities and Other Liabilities [Abstract]
Accrued Liabilities and Other Liabilities [Abstract]
Schedule of Cash and Cash Equivalents, Money Market Funds and Short-term Investments by Significant Investment Category
Cash, Cash Equivalent, and Investment [Table Text Block]
Underlying common stock fair value (USD per share)
Underlying Common Stock Fair Value
Underlying common stock fair value.
Debt Instrument, Redemption, Period [Axis]
Debt Instrument, Redemption, Period [Axis]
Adjustment to Compensation, Amount
Adjustment to Compensation Amount
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Outstanding stock option awards
Options to purchase common stock
Stock Options
Share-Based Payment Arrangement, Option [Member]
U.S. Government agency securities
US Government Corporations and Agencies Securities [Member]
Award Timing MNPI Disclosure
Award Timing MNPI Disclosure [Text Block]
Property, Plant and Equipment [Table]
Property, Plant and Equipment [Table]
Antidilutive Securities
Antidilutive Securities [Axis]
Incentive Stock Options and Nonqualified Stock Options
Incentive Stock Options And Nonqualified Stock Options [Member]
Incentive stock options and nonqualified stock options.
Total stockholders’ equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Accretion of final payment
Long-Term Debt, Accretion Of Final Payment
Long-Term Debt, Accretion Of Final Payment
Debt Securities, Available-for-sale [Table]
Debt Securities, Available-for-Sale [Table]
Measurement Frequency
Measurement Frequency [Axis]
Insider Trading Policies and Procedures [Line Items]
Stock options and ESPP
Employee Stock Option And Purchase Plan [Member]
Employee stock option and purchase plan.
Total stock-based compensation expense
Share-Based Payment Arrangement, Expense
Schedule of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
Issuance of common stock under benefit plans (in shares)
Stock Issued During Period, Shares, Employee Benefit Plan
Common stock issued in a public offering, net of offering expenses (in shares)
Stock Issued During Period, Shares, New Issues
Current assets
Assets, Current [Abstract]
Forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Total liabilities and stockholders’ equity
Liabilities and Equity
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Fair Value, Recurring
Fair Value, Recurring [Member]
Correlation coefficient
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions ; Correlation Coefficient
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions ; Correlation Coefficient
Number of Options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Liabilities and stockholders’ equity
Liabilities and Equity [Abstract]
Cover [Abstract]
Cover [Abstract]
2029 and thereafter
Lessee, Operating Lease, Liability, To Be Paid, Year Four And After Year Four
Lessee, Operating Lease, Liability, To Be Paid, Year Four And After Year Four
Maximum
Maximum [Member]
General and administrative expenses
General and Administrative Expense [Member]
Weighted- average exercise price per share, exercisable (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Accounting Policies [Abstract]
Accounting Policies [Abstract]
Schedule of Operating Lease Liability
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Non-PEO NEO Average Total Compensation Amount
Non-PEO NEO Average Total Compensation Amount
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Adjustment to Non-PEO NEO Compensation Footnote
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
Pay vs Performance Disclosure [Line Items]
Class of Warrant or Right [Axis]
Class of Warrant or Right [Axis]
Total discounted lease payments
Operating Lease, Liability
Retirement Benefits [Abstract]
Retirement Benefits [Abstract]
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Line of Credit Facility, Lender [Domain]
Line of Credit Facility, Lender [Domain]
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Liabilities measured at fair value
Financial Liabilities Fair Value Disclosure
Entity Shell Company
Entity Shell Company
Effective interest rate for the term loan
Long-Term Debt, Weighted Average Interest Rate, over Time
Schedule of Weighted-average Remaining Lease Terms and Discount Rates
Assets And Liabilities, Lessee [Table Text Block]
Assets And Liabilities, Lessee
Schedule of Long-Term Debt Instruments [Table]
Schedule of Long-Term Debt Instruments [Table]
Proceeds from term loan, net of issuance costs
Proceeds from Issuance of Debt
Debt Instrument, Redemption, Period [Domain]
Debt Instrument, Redemption, Period [Domain]
Statement of Stockholders' Equity [Abstract]
Statement of Stockholders' Equity [Abstract]
Common Stock, par value $0.0001 per share
Common Stock, Par Value $0.0001 Per Share [Member]
Common Stock, Par Value $0.0001 Per Share
Statement of Cash Flows [Abstract]
Statement of Cash Flows [Abstract]
Company Selected Measure Amount
Company Selected Measure Amount
2028
Lessee, Operating Lease, Liability, to be Paid, Year Three
Award Timing MNPI Considered
Award Timing MNPI Considered [Flag]
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Name
Measure Name
Restructuring reserve
Restructuring Reserve
Letter of Credit
Letter of Credit [Member]
Operating lease liabilities, current (Note 15)
Total current operating lease liabilities
Operating Lease, Liability, Current
Class of Stock [Line Items]
Class of Stock [Line Items]
Number of shares per right entitled to purchase (in shares)
Number Of Shares Per Right Entitled To Purchase
Number Of Shares Per Right Entitled To Purchase
Document Fiscal Period Focus
Document Fiscal Period Focus
Award Timing Method
Award Timing Method [Text Block]
Furniture and fixtures
Furniture and Fixtures [Member]
Award Type
Award Type [Axis]
Average peer group correlation coefficient
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions; Average Peer Group Correlation Coefficient
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions; Average Peer Group Correlation Coefficient
Number of classes of stock authorized
Number Of Classes Of Stock Authorized
Number Of Classes Of Stock Authorized
Long-term debt (Note 7)
Total
Long-Term Debt
Total assets
Assets
Employee-related expenses - research and development (excluding stock-based compensation)
Research And Development Expense, Adjusted
Research And Development Expense, Adjusted
Released (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Released, Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Released, Weighted Average Grant Date Fair Value
Trading Symbol
Trading Symbol
Geographical
Geographical [Domain]
Entity Address, City or Town
Entity Address, City or Town
Cash flows from operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Other segment items
Segment Reporting, Other Segment Item, Amount
Supplemental disclosures of cash flow information related to leases:
Additional Cash Flow Elements and Supplemental Cash Flow Information [Abstract]
Non-PEO NEO Average Compensation Actually Paid Amount
Non-PEO NEO Average Compensation Actually Paid Amount
Income Statement Location
Statement of Income Location, Balance [Domain]
Vesting of RSUs
Restricted Stock Units
Restricted stock units
Restricted Stock Units (RSUs) [Member]
Reconciliation of cash, cash equivalents, and restricted cash reported in the balance sheets
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation [Abstract]
Compensation Actually Paid vs. Other Measure
Compensation Actually Paid vs. Other Measure [Text Block]
Entity Emerging Growth Company
Entity Emerging Growth Company
2028
Long-Term Debt, Maturity, Year Three
Dividends declared (USD per share)
Common Stock, Dividends, Per Share, Declared
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Right-of-use assets obtained in exchange for new operating lease liabilities
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Debt Securities, Available-for-sale [Line Items]
Debt Securities, Available-for-Sale [Line Items]
Outstanding, beginning balance (in shares)
Outstanding, ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member]
2015 Equity and 2020 Incentive Plan
Two Thousand Fifteen And Two Thousand Twenty Equity Incentive Plan [Member]
Two thousand fifteen and two thousand twenty equity incentive plan .
Level 2
Fair Value, Inputs, Level 2 [Member]
Insider Trading Policies and Procedures Not Adopted
Insider Trading Policies and Procedures Not Adopted [Text Block]
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Common stock, shares outstanding (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Common Stock, Shares, Outstanding
Plan Name
Plan Name [Axis]
Document Information [Table]
Document Information [Table]
PEO
PEO [Member]
One Time Employee Severance
One Time Employee Severance [Member]
One Time Employee Severance
Number of common stock issued (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member]
Volatility
Expected stock price volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Accumulated Deficit
Retained Earnings [Member]
Prepaid expenses and other current assets (Note 5)
Total prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Restricted Stock Units
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Schedule of Accrued Liabilities
Schedule of Accrued Liabilities [Table Text Block]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Restatement Determination Date
Restatement Determination Date
Share-based Payment Arrangement [Abstract]
Share-Based Payment Arrangement [Abstract]
Cash and cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
Total cash, cash equivalents, and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Income Statement [Abstract]
Income Statement [Abstract]
Income tax provision
Income Tax Expense (Benefit)
Warrant, exercisable after beneficial ownership threshold announcement, number of days
Class Of Warrant Or Right, Exercisable After Beneficial Ownership Threshold Announcement, Number Of Days
Class Of Warrant Or Right, Exercisable After Beneficial Ownership Threshold Announcement, Number Of Days
Variable rate
Debt Instrument, Basis Spread on Variable Rate
Fair Value Measurements, Non-recurring Basis
Fair Value, Nonrecurring [Member]
Document Information [Line Items]
Document Information [Line Items]
Preferred stock, shares issued (in shares)
Preferred Stock, Shares Issued
Pension Adjustments Service Cost
Pension Adjustments Service Cost [Member]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Total property and equipment, gross
Property, Plant and Equipment, Gross
Restatement does not require Recovery
Restatement Does Not Require Recovery [Text Block]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Restructuring of Operations
Restructuring and Related Activities Disclosure [Text Block]
Non-cash operating lease expense
Operating Lease, Right-of-Use Asset, Periodic Reduction
Compensation Actually Paid vs. Company Selected Measure
Compensation Actually Paid vs. Company Selected Measure [Text Block]
City Area Code
City Area Code
Award Timing, How MNPI Considered
Award Timing, How MNPI Considered [Text Block]
All Trading Arrangements
All Trading Arrangements [Member]
Equity Awards Adjustments, Footnote
Equity Awards Adjustments, Footnote [Text Block]
Total Shareholder Return Vs Peer Group
Total Shareholder Return Vs Peer Group [Text Block]
Weighted- average remaining contractual term (in years), vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Accrued liabilities (Note 6)
Total accrued liabilities
Accrued Liabilities, Current
Outstanding and unvested, beginning balance (in shares)
Outstanding and unvested, ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Class of Warrant or Right [Line Items]
Class of Warrant or Right [Line Items]
Cash flows from investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
General and administrative
General and Administrative Expense
Unrecognized compensation cost
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Pay vs Performance Disclosure
Pay vs Performance Disclosure [Table]
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Market Value
Debt Securities, Available-for-Sale, Excluding Accrued Interest
Preferred stock, par value (USD per share)
Preferred Stock, Par or Stated Value Per Share
Schedule of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for Stock Option Awards
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Total expense
Lease, Cost
Equity Valuation Assumption Difference, Footnote
Equity Valuation Assumption Difference, Footnote [Text Block]
Schedule of Operating and Variable Lease Cost
Lease, Cost [Table Text Block]
PEO Total Compensation Amount
PEO Total Compensation Amount
Long-term Debt, Type [Axis]
Long-Term Debt, Type [Axis]
Depreciation expense
Depreciation
Weighted- average exercise price per share, vested and expected to vest (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Money Market Funds
Money Market Funds [Member]
Equity Components
Equity Components [Axis]
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Number of reportable segments
Number of Reportable Segments
Laboratory equipment
Equipment [Member]
Accrued research and development
Accrued Research And Development Expenses, Current
Accrued research and development expenses, current
Restructuring Cost and Reserve [Line Items]
Restructuring Cost and Reserve [Line Items]
Other Performance Measure, Amount
Other Performance Measure, Amount
Weighted- Average Exercise Price per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Entity Address, State or Province
Entity Address, State or Province
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Total current liabilities
Liabilities, Current
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]
Reduction in workforce, percent
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Individual:
Individual [Axis]
Payment made under defined contribution plan
Defined Contribution Plan, Cost
Restricted cash
Restricted Cash
Research and development expenses
Research and Development Expense [Member]
Additional paid-in capital
Additional Paid in Capital, Common Stock
Supplemental disclosures of cash flow information:
Supplemental Cash Flow Disclosures [Abstract]
Supplemental Cash Flow Disclosures Abstract
Net cash provided by investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member]
Cash paid for interest
Interest Paid, Excluding Capitalized Interest, Operating Activity
Document Fiscal Year Focus
Document Fiscal Year Focus
Stated interest rate plus variable rate floor
Debt Instrument, Stated Interest Rate Plus Variable Rate
Debt Instrument, Stated Interest Rate Plus Variable Rate
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Lender Name [Axis]
Lender Name [Axis]
Operating lease right-of-use assets (Note 15)
Operating Lease, Right-of-Use Asset
Forgone Recovery, Explanation of Impracticability
Forgone Recovery, Explanation of Impracticability [Text Block]
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent
Entity Interactive Data Current
Entity Interactive Data Current
Operating lease costs
Operating Lease, Cost
Plan Name
Plan Name [Domain]
Unrecognized compensation expense, weighted average period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Exercised (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Equity [Abstract]
Equity [Abstract]
Aggregate intrinsic value, exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Segments
Segment Reporting Disclosure [Text Block]
U.S. Treasury securities
US Treasury Securities [Member]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Class of Warrant or Right [Table]
Class of Warrant or Right [Table]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Landlord
Landlord [Member]
Landlord
Compensation Actually Paid vs. Total Shareholder Return
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
Other non-current assets
Other Assets, Noncurrent
Entity Central Index Key
Entity Central Index Key
PEO Name
PEO Name
Schedule of Maturities of Long-Term Debt
Schedule of Maturities of Long-Term Debt [Table Text Block]
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Outstanding Aggregate Erroneous Compensation Amount
Outstanding Aggregate Erroneous Compensation Amount
Schedule of Share-Based Payment Award, Equity Instruments Other Than Options, Valuation Assumptions
Schedule of Share-Based Payment Award, Equity Instruments Other Than Options, Valuation Assumptions [Table Text Block]
Schedule of Share-Based Payment Award, Equity Instruments Other Than Options, Valuation Assumptions
Comprehensive loss:
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Arrangement Duration
Trading Arrangement Duration
Schedule of Segment Reporting Information, by Segment [Table]
Schedule of Segment Reporting Information, by Segment [Table]
Expected volatility, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Financial Instruments
Financial Instruments Disclosure [Text Block]
Average peer group volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions; Average Peer Group Volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions; Average Peer Group Volatility
Segments [Axis]
Segments [Axis]
Exercise price (USD per share)
Class of Warrant or Right, Exercise Price of Warrants or Rights
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Exercise Price
Award Exercise Price
Entity Filer Category
Entity Filer Category
Local Phone Number
Local Phone Number
Class of Stock [Domain]
Class of Stock [Domain]
Additional 402(v) Disclosure
Additional 402(v) Disclosure [Text Block]
Unrecognized compensation cost
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Equity Incentive Plans and Stock-Based Compensation
Share-Based Payment Arrangement [Text Block]
Total for severance and related benefits for employees
Restructuring and Related Cost, Expected Cost
Assets
Assets [Abstract]
Credit Facility [Axis]
Credit Facility [Axis]
Maturity of short-term investments
Proceeds from Maturities, Prepayments and Calls of Short-Term Investments
Underlying Security Market Price Change
Underlying Security Market Price Change, Percent
Class of Warrant or Right [Domain]
Class of Warrant or Right [Domain]
Shares of common stock available for future grants under the 2022 Inducement Plan
Two Thousand And Twenty Two Inducement Plan [Member]
Two Thousand And Twenty Two Inducement Plan
Debt Instrument [Axis]
Debt Instrument [Axis]
Forfeited (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Credit Facility [Domain]
Credit Facility [Domain]
Stockholders’ equity
Equity, Attributable to Parent [Abstract]
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member]
Vesting rights, percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Entity Address, Address Line One
Entity Address, Address Line One
Research and development
Research and Development Expense
Accumulated Other Comprehensive Gain/(Loss)
AOCI Attributable to Parent [Member]
Stated percentage
Debt Instrument, Interest Rate, Stated Percentage
Operating lease liabilities, non-current (Note 15)
Total non-current operating lease liabilities
Operating Lease, Liability, Noncurrent
Reconciliation of segment loss
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Abstract]
Fair Value as of Grant Date
Award Grant Date Fair Value
Property, Plant and Equipment [Abstract]
Property, Plant and Equipment [Abstract]
Entity Registrant Name
Entity Registrant Name
Other non-current assets
Increase (Decrease) in Other Noncurrent Assets
Stock Price or TSR Estimation Method
Stock Price or TSR Estimation Method [Text Block]
Subsequent to Second Anniversary
Subsequent To Second Anniversary [Member]
Subsequent To Second Anniversary
Granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Thereafter
Long-Term Debt, Maturity, After Year Four
Long-Term Debt, Maturity, After Year Four
Document Quarterly Report
Document Quarterly Report
Assets measured at fair value
Assets, Fair Value Disclosure
Changed Peer Group, Footnote
Changed Peer Group, Footnote [Text Block]
Interest receivable
Interest Receivable, Current
Counterparty Name
Counterparty Name [Domain]
2027
Lessee, Operating Lease, Liability, to be Paid, Year Two
Number of operating segments
Number of Operating Segments
Adjustment To PEO Compensation, Footnote
Adjustment To PEO Compensation, Footnote [Text Block]
Weighted- average remaining contractual term (in years), outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Rights Agreement
Rights Agreement [Member]
Rights Agreement
Granted (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Title
Trading Arrangement, Individual Title
Peer Group Total Shareholder Return Amount
Peer Group Total Shareholder Return Amount
Temporary Equity Disclosure [Abstract]
Temporary Equity Disclosure [Abstract]
Restatement Determination Date:
Restatement Determination Date [Axis]
Non-PEO NEO
Non-PEO NEO [Member]
Aggregate intrinsic value, outstanding balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Name
Trading Arrangement, Individual Name
Award Type
Award Type [Domain]
2026
Lessee, Operating Lease, Liability, to be Paid, Year One
Equity Awards Adjustments
Equity Awards Adjustments [Member]
Leasehold improvements
Leasehold Improvements [Member]
Bexotegrast - clinical trial and third party contracting costs
Clinical Trial And Outside Service Third Party Contracting Costs
Clinical Trial And Outside Service Third Party Contracting Costs
Pension Benefits Adjustments, Footnote
Pension Benefits Adjustments, Footnote [Text Block]
Compensation Amount
Outstanding Recovery Compensation Amount
Term loan facility
Debt Instrument, Face Amount
Debt Instrument, Name [Domain]
Debt Instrument, Name [Domain]
Expected dividend
Expected dividends
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Recovery of Erroneously Awarded Compensation Disclosure [Line Items]
MNPI Disclosure Timed for Compensation Value
MNPI Disclosure Timed for Compensation Value [Flag]
Name
Awards Close in Time to MNPI Disclosures, Individual Name
Payments for restructuring
Payments for Restructuring
Unvested and outstanding, beginning balance (USD per share)
Unvested and outstanding, ending balance (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Restricted cash
Restricted Cash, Noncurrent
Restructuring Type [Axis]
Restructuring Type [Axis]
Aggregate Erroneous Compensation Not Yet Determined
Aggregate Erroneous Compensation Not Yet Determined [Text Block]
Term Loan Facility
Term Loan Facility [Member]
Term Loan Facility
Cash and cash equivalents
Cash Equivalents, at Carrying Value
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Leased premises under non cancelable operating lease
Leased Space Under Non Cancellable Operating Lease
Leased space under non cancellable operating lease.
Accumulated other comprehensive (loss) gain
Accumulated Other Comprehensive Income (Loss), Net of Tax
Aggregate intrinsic value, vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Financial Instruments [Domain]
Financial Instruments [Domain]
Segments [Domain]
Segments [Domain]
Income Statement Location
Statement of Income Location, Balance [Axis]
Aggregate Pension Adjustments Service Cost
Aggregate Pension Adjustments Service Cost [Member]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Minimum
Minimum [Member]
Less: Accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Target level of achievement percentage
Share-Based Compensation Arrangement By Share-Based Payment Award, Target Level Of Achievement Percentage
Share-Based Compensation Arrangement By Share-Based Payment Award, Target Level Of Achievement Percentage
First Anniversary
First Anniversary [Member]
First Anniversary
Company Selected Measure Name
Company Selected Measure Name
Long-term Debt
Debt Disclosure [Text Block]
Preferred stock, $0.0001 par value per share; 10,000,000 shares authorized at June 30, 2025 and December 31, 2024, 300,000 shares designated as Series A Junior Participating Preferred Stock at June 30, 2025 and none designated as Series A Junior Participating Preferred Stock at December 31, 2024; and none issued or outstanding at June 30, 2025 and December 31, 2024 (Note 8 and 10)
Preferred Stock, Value, Issued
Aggregate Available
Trading Arrangement, Securities Aggregate Available Amount
Accounts payable
Accounts Payable, Current
Stock Appreciation Rights (SARs)
Stock Appreciation Rights (SARs) [Member]
All Executive Categories
All Executive Categories [Member]
Common stock, $0.0001 par value per share; 300,000,000 shares authorized at June 30, 2025 and December 31, 2024; and 61,386,183 and 60,860,838 shares issued and outstanding at June 30, 2025 and December 31, 2024, respectively; (Note 9)
Common Stock, Value, Issued
Expected volatility, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Short-term investments
Short-Term Investments
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Prepaid research and development
Prepaid Research And Development, Current
Prepaid Research And Development, Current
Shares used in computing net loss per share - diluted (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Commitments and Contingencies (Note 14)
Commitments and Contingencies
No Trading Symbol Flag
No Trading Symbol Flag
Non-GAAP Measure Description
Non-GAAP Measure Description [Text Block]
Series A Junior Participating Preferred Purchase Rights
Series A Junior Participating Preferred Purchase Rights [Member]
Series A Junior Participating Preferred Purchase Rights
Other
Other Prepaid Expense, Current
Entity Small Business
Entity Small Business
Income Tax Disclosure [Abstract]
Income Tax Disclosure [Abstract]
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding
Document Transition Report
Document Transition Report
Performance-Based Restricted Stock Units
Performance-based restricted stock units
Performance-Based Restricted Stock Units [Member]
Performance-Based Restricted Stock Units
Short-term investments
Short-Term Investments [Member]
Underlying Securities
Award Underlying Securities Amount
Equity Component
Equity Component [Domain]
Document Period End Date
Document Period End Date
PEO Actually Paid Compensation Amount
PEO Actually Paid Compensation Amount
Cash and Cash Equivalents
Cash and Cash Equivalents [Domain]
Income Taxes
Income Tax Disclosure [Text Block]
Line of credit facility, current borrowing capacity
Proceeds from Lines of Credit
Awards Close in Time to MNPI Disclosures, Table
Awards Close in Time to MNPI Disclosures [Table Text Block]
Weighted- average remaining contractual term (in years), exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Defined Contribution Plan
Defined Contribution Plan [Text Block]
Document Type
Document Type
Fair Value, Inputs, Level 3
Fair Value, Inputs, Level 3 [Member]
Net Loss Per Share Attributable to Common Stockholders
Earnings Per Share [Text Block]
Name
Outstanding Recovery, Individual Name
Other accrued liabilities
Accounts Payable and Other Accrued Liabilities, Current
California
CALIFORNIA
Other variable costs
Variable Lease, Cost
All Individuals
All Individuals [Member]
Long-term Debt, Type [Domain]
Long-Term Debt, Type [Domain]
Fair Value Disclosures [Abstract]
Fair Value Disclosures [Abstract]
Warrant, Acquiring Person's beneficial ownership threshold, passive investor
Class Of Warrant Or Right, Acquiring Person's Beneficial Ownership Threshold, Passive Investor
Class Of Warrant Or Right, Acquiring Person's Beneficial Ownership Threshold, Passive Investor
Purchase of property and equipment
Payments to Acquire Property, Plant, and Equipment
Number of options, vested and expected to vest (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Name
Forgone Recovery, Individual Name
Expiration period from date of grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Total current assets
Assets, Current
Statistical Measurement
Statistical Measurement [Axis]
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member]
Interest rate in case of default
Debt Instrument, Interest Rate In Case Of Default
Debt Instrument, Interest Rate In Case Of Default
Common stock shares outstanding percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Common stock, voting rights, number of votes per share
Number Of Votes Per Each Share Of Common Stock
Number Of Votes Per Each Share Of Common Stock
Aggregate Erroneous Compensation Amount
Aggregate Erroneous Compensation Amount
Issuance of common stock under benefit plans
Stock Issued During Period, Value, Employee Benefit Plan
Peer Group Issuers, Footnote
Peer Group Issuers, Footnote [Text Block]
Erroneous Compensation Analysis
Erroneous Compensation Analysis [Text Block]
Total other comprehensive loss
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Current liabilities
Liabilities, Current [Abstract]
Weighted- Average Remaining Contractual Term (in Years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Geographical
Geographical [Axis]
Lessee, Lease, Description [Line Items]
Lessee, Lease, Description [Line Items]
Total operating expenses
Operating Expenses
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated [Flag]
Risk-free interest rate, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Line of credit
Long-Term Line of Credit
Level 1
Fair Value, Inputs, Level 1 [Member]
Accrued liabilities
Increase (Decrease) in Accrued Liabilities
Net loss per share - diluted (USD per share)
Earnings Per Share, Diluted
Erroneously Awarded Compensation Recovery
Erroneously Awarded Compensation Recovery [Table]
Title of 12(b) Security
Title of 12(b) Security
Lessee, Lease, Description [Table]
Lessee, Lease, Description [Table]
Supplemental disclosures of noncash investing and financing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Prepaid insurance
Prepaid Insurance
Earnings Per Share [Abstract]
Earnings Per Share [Abstract]
Organization and Description of Business
Business Description and Basis of Presentation [Text Block]
Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Accrued Liabilities
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Valuation date share price (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Exercise Price
Less: Present value discount
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Schedule of Shares Reserved for Future Issuance
Schedule Of Common Stock Reserved For Future Issuance Table [Table Text Block]
Schedule of common stock reserved for future issuance.
Employee stock purchase plan offering period
Employee Stock Purchase Plan Offering Period
Employee stock purchase plan offering period.
Exercised (USD per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Cash Equivalents
Cash Equivalents [Member]
Award Timing Disclosures [Line Items]
Shares of common stock available for future issuance under the 2020 Employee Stock Purchase Plan
2020 Employee Stock Purchase Plan
Two Thousand And Twenty Employee Stock Purchase Plan [Member]
Two thousand and twenty employee stock purchase plan.
Period in which options may be granted
Share Based Compensation Options Under Plan May Be Granted For Periods
Share based compensation options under plan may be granted for periods.
Total payments
Long-Term Debt, Gross
Granted (USD per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Accrued compensation and benefits
Employee-related Liabilities, Current
Measurement Frequency
Measurement Frequency [Domain]
Property and Equipment, net
Property, Plant and Equipment Disclosure [Text Block]
Future lease payments
Total undiscounted lease payments
Lessee, Operating Lease, Liability, to be Paid
Lease term extension period
Lessee, Operating Lease, Renewal Term
Net unrealized loss on short-term investments
Net unrealized loss on short-term investments
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Computer equipment and software
Computer Equipment And Software [Member]
Computer equipment and software.
Preferred Stock
Common Stock
Stockholder Rights Agreement
Equity [Text Block]
Net loss
Net loss
Net loss
Net Income (Loss) Attributable to Parent
General and administrative costs (excluding stock-based compensation)
General And Administrative Expense, Adjusted
General And Administrative Expense, Adjusted
Expiration Date
Trading Arrangement Expiration Date
Construction-in-progress
Construction in Progress [Member]
Vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Property and equipment, net (Note 4)
Total property and equipment, net
Property, Plant and Equipment, Net
Restructuring charges
Restructuring Charges
Segment Reporting Information [Line Items]
Segment Reporting Information [Line Items]
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized
Adoption Date
Trading Arrangement Adoption Date
Compensation Actually Paid vs. Net Income
Compensation Actually Paid vs. Net Income [Text Block]
Restructuring Cost [Table]
Restructuring Cost [Table]
Entity Current Reporting Status
Entity Current Reporting Status
Lease term
Lessee, Operating Lease, Term of Contract
Prepayment fee percentage
Debt Instrument, Prepayment Fee Percentage
Debt Instrument, Prepayment Fee Percentage
Awards Close in Time to MNPI Disclosures
Awards Close in Time to MNPI Disclosures [Table]
Loss from operations
Segment loss
Operating Income (Loss)
Percent of outstanding shares, shares added per year to plan
Percent Of Outstanding Shares, Shares Added Per Year To Plan
Percent Of Outstanding Shares, Shares Added Per Year To Plan
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Schedule of Classification of Stock-based Compensation Expense
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Net amortization (accretion) on short-term investments and debt
Accretion (Amortization) of Discounts And Premiums, Investments And Debt
Accretion (Amortization) of Discounts And Premiums, Investments And Debt
Financial Instrument [Axis]
Financial Instrument [Axis]
Statement of Financial Position [Abstract]
Statement of Financial Position [Abstract]
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member]
Executive Category:
Executive Category [Axis]
Valuation allowance as a percentage on total deferred tax assets
Valuation Allowance As Percentage On Deferred Tax Assets
Valuation allowance as percentage on deferred tax assets.
Current Fiscal Year End Date
Current Fiscal Year End Date
Class of Stock [Axis]
Class of Stock [Axis]
Expected term (in years)
Award term (years)
Expected term of options (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
2015 and 2020 Equity Incentive Plans and 2020 Inducement Plan
Two Thousand Fifteen And Two Thousand Twenty Equity Incentive Plans And Two Thousand Twenty Two Inducement Plan [Member]
Two Thousand Fifteen And Two Thousand Twenty Equity Incentive Plans And Two Thousand Twenty Two Inducement Plan
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member]
Proceeds from issuances of common stock under benefit plans
Proceeds From Issuances Of Common Stock Under Benefit Plans
Proceeds From Issuances Of Common Stock Under Benefit Plans
Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Statement [Table]
Statement [Table]
Percentage of payroll deductions
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Cash flows from financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Equity Awards Adjustments, Excluding Value Reported in Compensation Table
Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member]
Common stock fair market value percentage
Common Stock Fair Market Value Percentage
Common stock fair market value percentage .
Antidilutive securities excluded from computation of earnings per share (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Exercise price as a percentage of estimated grant date fair value of shares
Share Based Compensation Arrangement By Share Based Payment Award Exercise Price With Purchase Price Of Common Stock Percentage Of Estimated Grant Date Fair Value For Shareholders
Share based compensation arrangement by share based payment award exercise price with purchase price of common stock percentage of estimated grant date fair value for shareholders.
All Adjustments to Compensation
All Adjustments to Compensation [Member]
Fair Value, by Balance Sheet Grouping [Table]
Fair Value, by Balance Sheet Grouping [Table]
Amendment Flag
Amendment Flag
Leases
Lessee, Operating Leases [Text Block]
Termination Date
Trading Arrangement Termination Date
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Insider Trading Policies and Procedures Adopted
Insider Trading Policies and Procedures Adopted [Flag]
Measure:
Measure [Axis]
Weighted-average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Schedule of Option Activity Under the 2015 Plan and 2020 Plan
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Shares used in computing net loss per share - basic (in shares)
Weighted Average Number of Shares Outstanding, Basic
Number of options, exercisable (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Segment Reporting [Abstract]
Number of rights declared (in shares)
Dividend Distribution, Number Of Rights Declared
Dividend Distribution, Number Of Rights Declared
Pay vs Performance Disclosure, Table
Pay vs Performance [Table Text Block]
Debt Disclosure [Abstract]
Forgone Recovery due to Violation of Home Country Law, Amount
Forgone Recovery due to Violation of Home Country Law, Amount
Risk-free interest rate
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Second Anniversary
Second Anniversary [Member]
Second Anniversary
Entity Tax Identification Number
Entity Tax Identification Number
Prepaid Expenses and Other Current Assets
Prepaid Expenses And Other Current Assets [Text Block]
Prepaid Expenses And Other Current Assets
Outstanding, beginning balance (USD per share)
Outstanding, ending balance (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Restructuring and Related Activities [Abstract]
Forgone Recovery due to Expense of Enforcement, Amount
Forgone Recovery due to Expense of Enforcement, Amount
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Common stock, par value (USD per share)
Common Stock, Par or Stated Value Per Share
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
Weighted-average remaining lease term (in years)
Operating Lease, Weighted Average Remaining Lease Term
2029
Long-Term Debt, Maturity, Year Four
Reportable Segment
Reportable Segment [Member]
Reportable Segment
Granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Schedule of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for 2020 Employee Stock Purchase Plan
Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block]
Interest expense
Interest expense
Interest expense
Interest Expense, Nonoperating
Trading Arrangement:
Trading Arrangement [Axis]
Total Shareholder Return Amount
Total Shareholder Return Amount
Loan Agreement
Loan Agreement [Member]
Loan Agreement
Insider Trading Arrangements [Line Items]
Security Exchange Name
Security Exchange Name
Forfeited (USD per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Debt instrument final payment, percentage of original principal amount drawn
Debt Instrument Final Payment, Percentage Of Original Principal Amount Drawn
Debt Instrument Final Payment, Percentage Of Original Principal Amount Drawn
Total liabilities
Liabilities
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Cash and Cash Equivalents
Cash and Cash Equivalents [Axis]
Purchase of property and equipment in accounts payable and accrued liabilities
Capital Expenditures Incurred but Not yet Paid
Pension Adjustments Prior Service Cost
Pension Adjustments Prior Service Cost [Member]
Pliant Therapeutics
Pliant Therapeutics [Member]
Pliant Therapeutics
Operating expenses:
Operating expenses:
Operating Expenses [Abstract]
Material Terms of Trading Arrangement
Material Terms of Trading Arrangement [Text Block]
Contractual arrangements cancellation period
Contractual Arrangements Cancellation Period
Contractual arrangements cancellation period.
Statement [Line Items]
Statement [Line Items]
Less: unamortized debt issuance costs
Unamortized Debt Issuance Expense
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted [Flag]
Cash and cash equivalents
Cash and Cash Equivalent
Counterparty Name
Counterparty Name [Axis]
Schedule of Restricted Stock Activity
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Risk-free interest rate, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Common Stock
Common Stock [Member]
Vested (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Non-NEOs
Non-NEOs [Member]
Corporate debt securities
Corporate Debt Securities [Member]
Net increase in cash and cash equivalents
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Schedule of Prepaid Expenses and Other Current Assets
Schedule Of Prepaid Expenses And Other Current Assets [Table Text Block]
Schedule Of Prepaid Expenses And Other Current Assets