Supplemental disclosures of cash flow information related to leases:
Additional Cash Flow Elements and Supplemental Cash Flow Information [Abstract]
U.S. Government Agency Securities
US Government Corporations and Agencies Securities [Member]
Cash and cash equivalents
Cash And Cash Equivalents, At Carrying Value, Rounded
Cash And Cash Equivalents, At Carrying Value, Rounded
Operating Leases, After Adoption of 842:
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Integrin Research Target Program
Integrin Research Target Program [Member]
Integrin Research Target Program
Percentage of payroll deductions
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate
Weighted- average remaining contractual term (in years), vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Statistical Measurement
Statistical Measurement [Domain]
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Summary of Operating and Variable Lease Cost
Lease, Cost [Table Text Block]
Schedule of Cash and Cash Equivalents, Money Market Funds and Short-term Investments by Significant Investment Category
Cash, Cash Equivalents and Investments [Table Text Block]
Cover [Abstract]
Cover [Abstract]
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Net increase (decrease) in cash and cash equivalents
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Summary of Operating Lease Liability
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Debt Draw, Tranche Two
Debt Draw, Tranche Two [Member]
Debt Draw, Tranche Two
Released (in shares)
Share-Based Compensation Arrangement By Share-Based Payment Award, Equity Instruments Other Than Options, Releases in Period
Share-Based Compensation Arrangement By Share-Based Payment Award, Equity Instruments Other Than Options, Releases in Period
Income Tax Jurisdiction
Income Tax Jurisdiction [Domain]
Trading Symbol
Trading Symbol
Segment Reporting Information [Line Items]
Segment Reporting Information [Line Items]
All Trading Arrangements
All Trading Arrangements [Member]
2020 Stock Options and Incentive Plan and 2022 Inducement Plan
Two Thousand And Twenty Stock Options And Incentive Plan And Two Thousand Twenty Two Inducement Plan [Member]
Two Thousand And Twenty Stock Options And Incentive Plan And Two Thousand Twenty Two Inducement Plan
Debt Instrument, Redemption, Period [Axis]
Debt Instrument, Redemption, Period [Axis]
Compensation Actually Paid vs. Net Income
Compensation Actually Paid vs. Net Income [Text Block]
Non-NEOs
Non-NEOs [Member]
Vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Tax credits
Tax Credit Carryforward, Amount
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted [Flag]
Dividends declared (USD per share)
Common Stock, Dividends, Per Share, Declared
Awards Close in Time to MNPI Disclosures
Awards Close in Time to MNPI Disclosures [Table]
Performance-Based Restricted Stock Units, TSR Goal
Performance-Based Restricted Stock Units, TSR Goal [Member]
Performance-Based Restricted Stock Units, TSR Goal
Reclassification of restricted stock awards from liabilities to common stock upon vesting
Reclassification Of Restricted Stock Awards From Liabilities To Common Stock Upon Vesting
Reclassification of restricted stock awards from liabilities to common stock upon vesting.
Schedule of Classification of Stock-based Compensation Expense
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Pay vs Performance Disclosure [Line Items]
Peer Group Total Shareholder Return Amount
Peer Group Total Shareholder Return Amount
Short-term investments
Short-Term Investments [Member]
Interest and other income (expense), net
Interest and other (income) expense, net
Interest and Other Income (Expense), Net
Interest and Other Income (Expense), Net
Cash equivalents
Cash Equivalents [Member]
Debt Instrument, Redemption, Period [Domain]
Debt Instrument, Redemption, Period [Domain]
Accounts receivable
Increase (Decrease) in Accounts Receivable
Payment of offering costs
Payments Of Deferred Offering Costs
Represents the payments of deferred offering costs.
Net Loss Per Share
Earnings Per Share, Policy [Policy Text Block]
Operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Vesting of restricted stock awards (in shares)
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Shares of common stock available for future grants under the 2020 Stock Option and Incentive Plan
Two Thousand And Twenty Stock Options And Incentive Plan [Member]
2020 Stock options and incentive plan.
Prepaid licenses
Prepaid Licenses, Current
Prepaid Licenses, Current
Underlying common stock fair value (USD per share)
Underlying Common Stock Fair Value
Underlying common stock fair value.
Net unrealized (loss) gain on short-term investments
Net unrealized (loss) gain on short-term investments
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Award Timing Disclosures [Line Items]
Other Performance Measure, Amount
Other Performance Measure, Amount
Leases
Lessee, Operating Leases [Text Block]
Common stock, shares outstanding (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Common Stock, Shares, Outstanding
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Operating lease costs
Operating Lease, Cost
Forfeited (in shares)
Shares Issued, Shares, Share-Based Payment Arrangement, Forfeited
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Accounting policies.
Lease liabilities, non-current
Total non-current operating lease liabilities
Operating Lease, Liability, Noncurrent
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Segments
Segment Reporting, Policy [Policy Text Block]
Incentive Stock Options and Nonqualified Stock Options
Incentive Stock Options And Nonqualified Stock Options [Member]
Incentive stock options and nonqualified stock options.
Plan Name
Plan Name [Domain]
Accretion of final payment
Long-Term Debt, Accretion Of Final Payment
Long-Term Debt, Accretion Of Final Payment
Share price of shares issued (USD per share)
Sale of Stock, Price Per Share
Stock options and ESPP
Employee Stock Option And Purchase Plan [Member]
Employee stock option and purchase plan.
Issuance of common stock under benefit plans
Stock Issued During Period, Value, Employee Benefit Plan
Other non-current assets
Other Assets, Noncurrent
Entity Tax Identification Number
Entity Tax Identification Number
Leases [Abstract]
Leases [Abstract]
(Reductions) additions for tax positions of prior year
Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Correlation coefficient
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions ; Correlation Coefficient
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions ; Correlation Coefficient
Issuance of common stock under benefit plans (in shares)
Stock Issued During Period, Shares, Employee Benefit Plan
Money Market Funds
Money Market Funds [Member]
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
Proceeds from the sale of shares
Sale of Stock, Consideration Received on Transaction
Cash flows from operating activities
Net Cash Provided by (Used in) Operating Activities [Abstract]
U.S. Treasury securities
US Treasury Securities [Member]
Plan Name
Plan Name [Axis]
Equity Components
Equity Components [Axis]
Award Timing Method
Award Timing Method [Text Block]
Research and Development Expenses
Research and Development Expense, Policy [Policy Text Block]
Trading Arrangements, by Individual
Trading Arrangements, by Individual [Table]
Novartis Agreement
Novartis Agreement [Member]
Novartis agreement.
Defined Contribution Plan
Defined Contribution Plan [Text Block]
Measurement Frequency
Measurement Frequency [Axis]
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Insider Trading Policies and Procedures [Line Items]
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Adjustment to Compensation, Amount
Adjustment to Compensation Amount
Aggregate intrinsic value, outstanding balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Additional paid-in capital
Additional Paid in Capital, Common Stock
Compensation Amount
Outstanding Recovery Compensation Amount
Summary of Weighted-average Remaining Lease Terms and Discount Rates
Assets And Liabilities, Lessee [Table Text Block]
Assets And Liabilities, Lessee
Supplemental disclosures of noncash investing and financing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member]
Entity Small Business
Entity Small Business
Accrued Liabilities
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Company Selected Measure Amount
Company Selected Measure Amount
Geographical
Geographical [Axis]
Third Rock Ventures
Third Rock Ventures [Member]
Third Rock Ventures.
Tabular List, Table
Tabular List [Table Text Block]
2029
Lessee, Operating Lease, Liability, to be Paid, Year Five
Increases recorded to income tax provision
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Fair Value, Inputs, Level 3
Fair Value, Inputs, Level 3 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member]
Lessee, Lease, Description [Line Items]
Lessee, Lease, Description [Line Items]
Debt Securities, Available-for-sale [Line Items]
Debt Securities, Available-for-Sale [Line Items]
Accrued liabilities (Note 6)
Total accrued liabilities
Accrued Liabilities, Current
Total
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Impairment of long-lived assets
Impairment of Long-Lived Assets to be Disposed of
Impairment of Long-Lived Assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Credit Facility [Domain]
Credit Facility [Domain]
Cash, cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
Total cash, cash equivalents, and restricted cash shown in the statements of cash flows
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Current assets
Assets, Current [Abstract]
Average peer group correlation coefficient
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions; Average Peer Group Correlation Coefficient
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions; Average Peer Group Correlation Coefficient
Number of classes of stock authorized
Number Of Classes Of Stock Authorized
Number Of Classes Of Stock Authorized
Employee-related expenses - research and development (excluding stock-based compensation)
Research And Development Expense, Adjusted
Research And Development Expense, Adjusted
Released (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Released, Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Released, Weighted Average Grant Date Fair Value
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Product and Service
Product and Service [Domain]
Outstanding stock options
Options to purchase common stock
Share-Based Payment Arrangement, Option [Member]
Debt Securities, Available-for-sale [Table]
Debt Securities, Available-for-Sale [Table]
Weighted-Average Grant Date fair value, Vested (USD per share)
Weighted-average grant date fair value, vested (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Fair Value Disclosures [Abstract]
Fair Value Disclosures [Abstract]
Depreciation expense
Depreciation
2025
Lessee, Operating Lease, Liability, to be Paid, Year One
Antidilutive Security, Excluded EPS Calculation [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding
Security Exchange Name
Security Exchange Name
Loan agreement interest rate
Debt Instrument, Basis Spread on Variable Rate
Schedule of Remaining Contractual Maturities of Company’s Short-term Investments
Investments Classified by Contractual Maturity Date [Table Text Block]
Award Type
Award Type [Axis]
Related Party Transaction
Related Party Transaction [Domain]
Corporate debt securities
Corporate Debt Securities [Member]
Exercised (USD per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Cash and Cash Equivalents, Restricted Cash
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
2015 Equity and 2020 Incentive Plan
Two Thousand Fifteen And Two Thousand Twenty Equity Incentive Plan [Member]
Two thousand fifteen and two thousand twenty equity incentive plan .
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Property and equipment, net
Total property and equipment, net
Property, Plant and Equipment, Net
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Total liabilities
Liabilities
Dividends paid (USD per share)
Common Stock, Dividends, Per Share, Cash Paid
Weighted- average exercise price per share, exercisable (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Comprehensive loss:
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Common stock, par value (USD per share)
Common Stock, Par or Stated Value Per Share
Forgone Recovery, Explanation of Impracticability
Forgone Recovery, Explanation of Impracticability [Text Block]
Research and development
Research and Development Expense
Grant date fair value of stock option
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Fair Value
Share based compensation arrangement by share based payment award options grants in period fair value.
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Employee stock purchase plan, description
Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award
Investment, Type [Extensible Enumeration]
Investment, Type [Extensible Enumeration]
Expiration Date
Trading Arrangement Expiration Date
Fair Value Measurements, Non-recurring Basis
Fair Value, Nonrecurring [Member]
Cash flows from investing activities
Net Cash Provided by (Used in) Investing Activities [Abstract]
Lease liabilities, current
Total current operating lease liabilities
Operating Lease, Liability, Current
Total Shareholder Return Amount
Total Shareholder Return Amount
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
Preferred Stock
Redeemable Convertible Preferred Stock [Text Block]
Redeemable convertible preferred stock.
Equity Awards Adjustments, Footnote
Equity Awards Adjustments, Footnote [Text Block]
Net operating losses
Deferred Tax Assets, Operating Loss Carryforwards
Accrued Liabilities and Other Liabilities [Abstract]
Accrued Liabilities and Other Liabilities [Abstract]
Laboratory equipment
Equipment [Member]
Insider Trading Policies and Procedures Adopted
Insider Trading Policies and Procedures Adopted [Flag]
Less: Accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Prepaid insurance
Prepaid Insurance
Total property and equipment, gross
Property, Plant and Equipment, Gross
Exercised (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Named Executive Officers, Footnote
Named Executive Officers, Footnote [Text Block]
Research and development expenses
Research and Development Expense [Member]
Weighted- Average Exercise Price per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
Effective interest rate for the term loan
Long-Term Debt, Weighted Average Interest Rate, over Time
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Weighted average shares used in computing net loss per share - diluted (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Mature in 1 to 2 years
Mature In One To Two Years [Member]
Mature in one to two years.
MNPI Disclosure Timed for Compensation Value
MNPI Disclosure Timed for Compensation Value [Flag]
Long-Term Debt, Type [Axis]
Long-Term Debt, Type [Axis]
Total stockholders’ equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Total deferred tax assets
Deferred Tax Assets, Gross
Entity Voluntary Filers
Entity Voluntary Filers
Proceeds from term loan, net of issuance costs
Proceeds from Issuance of Debt
Novartis Collaboration and License Agreement (the "Novartis Agreement")
Collaborative Arrangement Disclosure [Text Block]
Financial Instruments
Financial Instruments Disclosure [Text Block]
Lease term extension period
Lessee, Operating Lease, Renewal Term
Interest expense
Interest expense
Interest Expense, Nonoperating
Repurchase Agreements and Similar Transactions, Maturity Periods
Repurchase Agreements and Similar Transactions, Maturity Periods [Axis]
Property and Equipment, net
Property, Plant and Equipment Disclosure [Text Block]
Accounting Standards Update and Change in Accounting Principle [Table]
Accounting Standards Update and Change in Accounting Principle [Table]
Payment made under defined contribution plan
Defined Contribution Plan, Cost
Total other comprehensive (loss) gain
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Fair Value, Recurring
Fair Value, Recurring [Member]
Accounts receivable, current
Accounts Receivable, after Allowance for Credit Loss, Current
Granted (in shares)
Options granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Sale of Stock
Sale of Stock [Domain]
Long-term debt (Note 7)
Total
Long-Term Debt
Pension Adjustments Prior Service Cost
Pension Adjustments Prior Service Cost [Member]
Document Fiscal Period Focus
Document Fiscal Period Focus
Performance Stock Units
Performance Stock Units [Member]
Performance Stock Units
2028
Long-Term Debt, Maturity, Year Four
All Executive Categories
All Executive Categories [Member]
Thereafter
Long-Term Debt, Maturity, after Year Five
Underwriters
Underwriters [Member]
Underwriters.
Changed Peer Group, Footnote
Changed Peer Group, Footnote [Text Block]
Weighted- average remaining contractual term (in years), outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Assets
Assets [Abstract]
Fair Value, by Balance Sheet Grouping [Table]
Fair Value, by Balance Sheet Grouping [Table]
Expected dividends
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Document Type
Document Type
Temporary Equity Disclosure [Abstract]
Temporary Equity Disclosure [Abstract]
Pension Benefits Adjustments, Footnote
Pension Benefits Adjustments, Footnote [Text Block]
Schedule of Segment Reporting Expenses
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Total Shareholder Return Vs Peer Group
Total Shareholder Return Vs Peer Group [Text Block]
Document Annual Report
Document Annual Report
Weighted- average remaining contractual term (in years), exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Percentage of revenue contributed by related party
Percentage Of Revenue Contributed By Related Party
Percentage of revenue contributed by related party.
Remaining PSU vested (in shares)
Vested (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Valuation date share price (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Exercise Price
Risk free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Maximum
Maximum [Member]
Accrued research and development
Accrued Research And Development Expenses, Current
Accrued research and development expenses, current
Equity Valuation Assumption Difference, Footnote
Equity Valuation Assumption Difference, Footnote [Text Block]
Furniture and Fixture
Furniture and Fixtures [Member]
Antidilutive Securities
Antidilutive Securities [Axis]
Accounts payable
Accounts Payable, Current
Accounting Policies [Abstract]
Accounting Policies [Abstract]
Leasehold improvements
Leasehold Improvements [Member]
Schedule of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for Stock Option Awards
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Fair Value Measurements
Fair Value Measurement, Policy [Policy Text Block]
Current Fiscal Year End Date
Current Fiscal Year End Date
Related party transaction amount
Related Party Transaction, Amounts of Transaction
Less: Present value discount
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Total expense
Lease, Cost
Before January 1, 2018
Before January12018 [Member]
Before January 1,2018.
Other accrued liabilities
Accounts Payable and Other Accrued Liabilities, Current
Short-term investments
Short-Term Investments
Statistical Measurement
Statistical Measurement [Axis]
PEO Name
PEO Name
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Number of common stock issued (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
Non-PEO NEO Average Total Compensation Amount
Non-PEO NEO Average Total Compensation Amount
Award Type
Award Type [Domain]
Name
Outstanding Recovery, Individual Name
Schedule of Changes in Valuation Allowance for Deferred Tax Assets
Summary of Valuation Allowance [Table Text Block]
Supplemental disclosures of cash flow information:
Supplemental Cash Flow Disclosures [Abstract]
Supplemental Cash Flow Disclosures
Stock based compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Other variable costs
Variable Lease, Cost
Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Compensation Actually Paid vs. Company Selected Measure
Compensation Actually Paid vs. Company Selected Measure [Text Block]
Non-PEO NEO
Non-PEO NEO [Member]
Title and Position
Title and Position [Axis]
Stated interest rate plus variable rate floor
Debt Instrument, Stated Interest Rate Plus Variable Rate
Debt Instrument, Stated Interest Rate Plus Variable Rate
Additional Paid-In Capital
Additional Paid-in Capital [Member]
Minimum cash balance, percentage of outstanding principal
Debt Instrument, Covenant, Minimum Cash Balance, Percentage Of Outstanding Principal
Debt Instrument, Covenant, Minimum Cash Balance, Percentage Of Outstanding Principal
Award Timing Predetermined
Award Timing Predetermined [Flag]
Novartis
Novartis [Member]
Novartis.
Class of Stock [Line Items]
Class of Stock [Line Items]
Restricted cash
Restricted Cash, Noncurrent
Recently Adopted Accounting Pronouncements and Recently Announced Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Forecast
Forecast [Member]
Diluted (USD per share)
Earnings Per Share, Diluted
Title and Position
Title and Position [Domain]
Counterparty Name
Counterparty Name [Domain]
Revenue Recognition
Revenue from Contract with Customer [Policy Text Block]
Non-cash operating lease expense
Operating Lease, Right-of-Use Asset, Periodic Reduction
Name
Measure Name
State
State and Local Jurisdiction [Member]
Pre-tax U.S. book loss
Income (Loss) from Continuing Operations before Income Taxes, Domestic
Entity Interactive Data Current
Entity Interactive Data Current
Restatement does not require Recovery
Restatement Does Not Require Recovery [Text Block]
Vesting rights, percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Number of operating segments
Number of Operating Segments
Retirement Benefits [Abstract]
Retirement Benefits [Abstract]
Deferred tax liabilities:
Deferred Tax Liabilities, Gross [Abstract]
Preferred stock, shares issued
Preferred Stock, Shares Issued
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Statement of Financial Position [Abstract]
Statement of Financial Position [Abstract]
Landlord
Landlord [Member]
Landlord
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Net deferred taxes
Deferred Tax Assets, Net of Valuation Allowance
Income tax provision
Income Tax Expense (Benefit)
Mature in 1 year or less
Mature In One Year Or Less [Member]
Mature in one year or less.
Interest rate, stated percentage
Debt Instrument, Interest Rate, Stated Percentage
Unrecognized compensation expense, weighted average period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Schedule of Share-Based Payment Award, Equity Instruments Other Than Options, Valuation Assumptions
Schedule of Share-Based Payment Award, Equity Instruments Other Than Options, Valuation Assumptions [Table Text Block]
Schedule of Share-Based Payment Award, Equity Instruments Other Than Options, Valuation Assumptions
Revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Research and development credits
Deferred Tax Asset, In-Process Research and Development
Average peer group volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions; Average Peer Group Volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions; Average Peer Group Volatility
Auditor Firm ID
Auditor Firm ID
Effective income tax rate
Effective Income Tax Rate Reconciliation, Percent
Net cash provided by (used in) investing activities
Net Cash Provided by (Used in) Investing Activities
Loss from operations
Loss from operations
Operating Income (Loss)
Income Tax Jurisdiction
Income Tax Jurisdiction [Axis]
Number of reportable segments
Number of Reportable Segments
Total liabilities and stockholders’ equity
Liabilities and Equity
Subsequent Event
Subsequent Events [Text Block]
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated [Flag]
All Adjustments to Compensation
All Adjustments to Compensation [Member]
Accrued compensation and benefits
Employee-related Liabilities, Current
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Shares of common stock available for future issuance under the 2022 Inducement Plan
Two Thousand And Twenty Two Inducement Plan [Member]
Two Thousand And Twenty Two Inducement Plan
Schedule of Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Schedule of Maturities of Long-Term Debt
Schedule of Maturities of Long-Term Debt [Table Text Block]
Amount subject to lender's discretion
Line Of Credit, Amount Subject To Lender's Discretion
Line Of Credit, Amount Subject To Lender's Discretion
Right-of-use assets obtained in exchange for new operating lease liabilities
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Outstanding amount threshold, maximum collateral requirement
Debt Instrument, Covenant, Outstanding Amount Threshold, Maximum Collateral Requirement
Debt Instrument, Covenant, Outstanding Amount Threshold, Maximum Collateral Requirement
Underlying Security Market Price Change
Underlying Security Market Price Change, Percent
Scenario [Domain]
Scenario [Domain]
Individual:
Individual [Axis]
Related Party Transaction
Related Party Transaction [Axis]
Vesting of restricted stock awards
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures
Accumulated Other Comprehensive (Loss) Gain
AOCI Attributable to Parent [Member]
Forfeited (USD per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Restricted cash
Restricted Cash
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Product and Service
Product and Service [Axis]
Long-Term Debt, Type [Domain]
Long-Term Debt, Type [Domain]
Entity Address, State or Province
Entity Address, State or Province
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Statement [Line Items]
Statement [Line Items]
Term loan balance threshold for minimum cash balance covenant
Debt Instrument, Covenant, Term Loan Balance Threshold For Minimum Cash Balance Covenant
Debt Instrument, Covenant, Term Loan Balance Threshold For Minimum Cash Balance Covenant
Repurchase Agreements and Similar Transactions, Maturity Periods
Repurchase Agreements and Similar Transactions, Maturity Periods [Domain]
Erroneous Compensation Analysis
Erroneous Compensation Analysis [Text Block]
Operating expenses:
Operating Expenses [Abstract]
Schedule of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
Compensation Actually Paid vs. Total Shareholder Return
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
Financial Instruments [Domain]
Financial Instruments [Domain]
Description of customer payment terms
Revenue, Performance Obligation, Description of Payment Terms
Subsequent To Second Anniversary
Subsequent To Second Anniversary [Member]
Subsequent To Second Anniversary
Weighted-Average Grant Date fair value, Outstanding and unvested, beginning balance (USD per share)
Weighted-Average Grant Date fair value, Outstanding and unvested, ending balance (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Liabilities and stockholders’ equity
Liabilities and Equity [Abstract]
Section 162(m)
Effective Income Tax Rate Reconciliation, Nondeductible, Executive Compensation Section, 162(m) Limitation
Effective Income Tax Rate Reconciliation, Nondeductible, Executive Compensation Section, 162(m) Limitation
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Line of credit facility, conditional borrowing capacity
Line Of Credit Facility, Conditional Borrowing Capacity
Line Of Credit Facility, Conditional Borrowing Capacity
Minimum
Minimum [Member]
Restatement Determination Date
Restatement Determination Date
Number of options, vested and expected to vest (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Number of income tax examinations pending
Income Tax Examination Number Of Examinations Pending
Income tax examination, number pending.
Less: unamortized debt issuance costs
Unamortized Debt Issuance Expense
Adoption Date
Trading Arrangement Adoption Date
Pay vs Performance Disclosure
Pay vs Performance Disclosure [Table]
Related Party Transactions [Abstract]
Related Party Transactions [Abstract]
Property, Plant and Equipment [Table]
Property, Plant and Equipment [Table]
Outstanding, beginning balance (USD per share)
Outstanding, ending balance (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Operating lease right-of-use assets
Operating Lease, Right-of-Use Asset
Erroneously Awarded Compensation Recovery
Erroneously Awarded Compensation Recovery [Table]
Outstanding, beginning balance (in shares)
Outstanding, ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Segments [Axis]
Segments [Axis]
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member]
Tax Period
Tax Period [Axis]
Income tax computed at federal statutory rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Property, Plant and Equipment [Abstract]
Property, Plant and Equipment [Abstract]
Total
Long-Term Debt, Gross
Exercise Price
Award Exercise Price
California
CALIFORNIA
Schedule of Deferred Tax Assets and Liabilities
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Liabilities measured at fair value
Financial Liabilities Fair Value Disclosure
Net Loss Per Share Attributable to Common Stockholders
Earnings Per Share [Text Block]
Arrangement Duration
Trading Arrangement Duration
Net operating losses
Operating Loss Carryforwards
Number of Integrin research targets
Number Of Integrin Research Targets
Number of Integrin research targets.
Schedule of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for 2020 Employee Stock Purchase Plan
Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block]
Stockholders’ equity
Equity, Attributable to Parent [Abstract]
Granted (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Federal
Domestic Tax Jurisdiction [Member]
Bexotegrast - clinical trial and outside service third party contracting costs
Clinical Trial And Outside Service Third Party Contracting Costs
Clinical Trial And Outside Service Third Party Contracting Costs
Income Taxes
Income Tax, Policy [Policy Text Block]
Peer Group Issuers, Footnote
Peer Group Issuers, Footnote [Text Block]
Segments [Domain]
Segments [Domain]
Material Terms of Trading Arrangement
Material Terms of Trading Arrangement [Text Block]
Unrecognized Tax Benefits [Roll Forward]
Unrecognized Tax Benefits [Roll Forward]
Accounting Policies [Table]
Accounting Policies [Table]
Accounting policies.
All Individuals
All Individuals [Member]
Line of credit facility, current borrowing capacity
Proceeds from Lines of Credit
PEO
PEO [Member]
Income Tax Disclosure [Abstract]
Income Tax Disclosure [Abstract]
Name
Trading Arrangement, Individual Name
Deferred Tax Assets, Valuation Allowance [Roll Forward]
Deferred Tax Assets, Valuation Allowance [Roll Forward]
Deferred Tax Assets, Valuation Allowance
Term Loan Facility
Term Loan Facility [Member]
Term Loan Facility
Statement of Stockholders' Equity [Abstract]
Statement of Stockholders' Equity [Abstract]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Entity Public Float
Entity Public Float
Leased premises under non cancelable operating lease
Leased Space Under Non Cancellable Operating Lease
Leased space under non cancellable operating lease.
Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Other non-current assets
Increase (Decrease) in Other Noncurrent Assets
Stock-based compensation
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Percent
Reconciliation of cash, cash equivalents, and restricted cash reported in the balance sheets
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations [Abstract]
Awards Close in Time to MNPI Disclosures, Table
Awards Close in Time to MNPI Disclosures [Table Text Block]
Lender Name [Axis]
Lender Name [Axis]
Total shares reserved for future issuance (in shares)
Common Stock, Capital Shares Reserved for Future Issuance
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member]
Related Party
Related and Nonrelated Parties [Domain]
Aggregate Erroneous Compensation Amount
Aggregate Erroneous Compensation Amount
Schedule of Net Operating Losses and Tax Credit Carryforwards
Schedule Of Net Operating Losses And Tax Credit Carryforwards Table [Table Text Block]
Tabular disclosure of net operating losses and tax credit carryforwards.
Target level of achievement percentage
Share-Based Compensation Arrangement By Share-Based Payment Award, Target Level Of Achievement Percentage
Share-Based Compensation Arrangement By Share-Based Payment Award, Target Level Of Achievement Percentage
First Anniversary
First Anniversary [Member]
First Anniversary
Local Phone Number
Local Phone Number
Valuation allowance
Valuation allowance at the beginning of the year
Valuation allowance at the end of the year
Deferred Tax Assets, Valuation Allowance
Aggregate Erroneous Compensation Not Yet Determined
Aggregate Erroneous Compensation Not Yet Determined [Text Block]
Total operating expenses
Operating Expenses
Net unrealized (loss) gain on short-term investments
Unrealized Gain (Loss) on Investments
Volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Risk-free interest rate, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Schedule of Restricted Stock Activity
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
PEO Total Compensation Amount
PEO Total Compensation Amount
Prepaid research and development
Prepaid Research And Development, Current
Prepaid Research And Development, Current
Market Value
Debt Securities, Available-for-Sale, Excluding Accrued Interest
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Schedule of Accrued Liabilities
Schedule of Accrued Liabilities [Table Text Block]
Statement of Income Location, Balance
Statement of Income Location, Balance [Axis]
Weighted- average exercise price per share, vested and expected to vest (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Debt Disclosure [Abstract]
Prepaid expenses
Deferred Tax Liabilities, Prepaid Expenses
Common Stock
Common Stock [Member]
Measure:
Measure [Axis]
Additions based on tax positions related to current year
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Operating Loss Carryforwards [Table]
Operating Loss Carryforwards [Table]
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized
Forgone Recovery due to Expense of Enforcement, Amount
Forgone Recovery due to Expense of Enforcement, Amount
Common stock issued in a public offering, net of offering expenses (in shares)
Stock Issued During Period, Shares, New Issues
Entity Emerging Growth Company
Entity Emerging Growth Company
Performance-based restricted stock units
Performance-Based Restricted Stock Units [Member]
Performance-Based Restricted Stock Units
Debt Draw Period [Axis]
Debt Draw Period [Axis]
Debt Draw Period
Segment Reporting [Abstract]
Eric Lefebvre [Member]
Eric Lefebvre
Entity Central Index Key
Entity Central Index Key
Other permanent differences
Effective Income Tax Rate Reconciliation, Tax Settlement, Other, Percent
2029
Long-Term Debt, Maturity, Year Five
Scenario [Axis]
Scenario [Axis]
Other segment items
Segment Reporting, Other Segment Item, Amount
Starting from January 1, 2018
Starting From January12018 [Member]
Starting from January 1, 2018.
General and administrative expenses
General and Administrative Expense [Member]
Lessee, Lease, Description [Table]
Lessee, Lease, Description [Table]
Non-GAAP Measure Description
Non-GAAP Measure Description [Text Block]
Non-PEO NEO Average Compensation Actually Paid Amount
Non-PEO NEO Average Compensation Actually Paid Amount
Common stock, voting rights
Number Of Votes Per Share Of Common Stock
Number Of Votes Per Share Of Common Stock
Expected volatility, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Common Stock
Equity [Text Block]
Award Timing, How MNPI Considered
Award Timing, How MNPI Considered [Text Block]
Equity Component
Equity Component [Domain]
Preferred stock, par value (USD per share)
Preferred Stock, Par or Stated Value Per Share
Financial Instrument [Axis]
Financial Instrument [Axis]
Segment
Segment Reporting Disclosure [Text Block]
General business credit—federal
Effective Income Tax Rate Reconciliation General Business Tax Credits Federal
Effective income tax rate reconciliation general business tax credits federal.
Interest receivable
Interest Receivable, Current
Additional 402(v) Disclosure
Additional 402(v) Disclosure [Text Block]
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Entity Shell Company
Entity Shell Company
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Restricted cash
Restricted Cash Equivalents
Comprehensive Loss
Comprehensive Income, Policy [Policy Text Block]
Title
Trading Arrangement, Individual Title
Statement [Table]
Statement [Table]
Measurement Frequency
Measurement Frequency [Domain]
Counterparty Name
Counterparty Name [Axis]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
January 1
December 31
Unrecognized Tax Benefits
Interest rate in case of default
Debt Instrument, Interest Rate In Case Of Default
Debt Instrument, Interest Rate In Case Of Default
City Area Code
City Area Code
Current liabilities
Liabilities, Current [Abstract]
Auditor Location
Auditor Location
Accrued expenses
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Cash paid for interest
Interest Paid, Excluding Capitalized Interest, Operating Activities
Insider Trading Policies and Procedures Not Adopted
Insider Trading Policies and Procedures Not Adopted [Text Block]
Customer payment term duration
Customer Payment Term Duration
Customer Payment Term Duration
Purchase of short-term investments
Payments to Acquire Short-Term Investments
Level 1
Fair Value, Inputs, Level 1 [Member]
Amount undrawn
Debt Instrument, Amount Undrawn
Debt Instrument, Amount Undrawn
Total current assets
Assets, Current
Non-employee Director
Nonemployee Director [Member]
Nonemployee Director.
Public Offering
Public Offering [Member]
Public Offering
Statement of Cash Flows [Abstract]
Statement of Cash Flows [Abstract]
Public Offering And Private Placement
Public Offering And Private Placement [Member]
Public Offering And Private Placement
Accrued liabilities
Increase (Decrease) in Accrued Liabilities
Tax Period
Tax Period [Domain]
Line of credit facility, remaining borrowing capacity
Line of Credit Facility, Remaining Borrowing Capacity
Number of options, exercisable (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Schedule of Long-Term Debt Instruments [Table]
Schedule of Long-Term Debt Instruments [Table]
Schedule of Segment Reporting Information, by Segment [Table]
Schedule of Segment Reporting Information, by Segment [Table]
Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Grant date fair value of stock option (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Income Taxes
Income Tax Disclosure [Text Block]
2028
Lessee, Operating Lease, Liability, to be Paid, Year Four
Earnings Per Share [Abstract]
Earnings Per Share [Abstract]
Equity [Abstract]
Equity [Abstract]
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Valuation Allowance [Abstract]
Valuation Allowance [Abstract]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
General and administrative
General and Administrative Expense
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Aggregate Available
Trading Arrangement, Securities Aggregate Available Amount
Equity Awards Adjustments
Equity Awards Adjustments [Member]
Weighted-average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease liability
Total discounted lease payments
Operating Lease, Liability
Net cash provided by financing activities
Net Cash Provided by (Used in) Financing Activities
Underlying Securities
Award Underlying Securities Amount
Credit Facility [Axis]
Credit Facility [Axis]
Operating Loss Carryforwards [Line Items]
Operating Loss Carryforwards [Line Items]
Amendment Flag
Amendment Flag
Entity Registrant Name
Entity Registrant Name
Lease liability
Deferred Tax Assets, Lease Liability
Deferred Tax Assets, Lease Liability
Adjustment to Non-PEO NEO Compensation Footnote
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
Stock Appreciation Rights (SARs)
Stock Appreciation Rights (SARs) [Member]
Schedule of Shares Reserved for Future Issuance
Schedule Of Common Stock Reserved For Future Issuance Table [Table Text Block]
Schedule of common stock reserved for future issuance.
Fair Value as of Grant Date
Award Grant Date Fair Value
Subsequent Events [Abstract]
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]
Employee stock purchase plan offering period
Employee Stock Purchase Plan Offering Period
Employee stock purchase plan offering period.
Aggregate intrinsic value, vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Level 2
Fair Value, Inputs, Level 2 [Member]
Public and private offering, shares issued (in shares)
Sale of Stock, Number of Shares Issued in Transaction
Debt
Debt Disclosure [Text Block]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Geographical
Geographical [Domain]
Recovery of Erroneously Awarded Compensation Disclosure [Line Items]
Term loan facility
Debt Instrument, Face Amount
Shares of common stock available for future issuance under the 2020 ESPP
2020 Employee Stock Purchase Plan
Two Thousand And Twenty Employee Stock Purchase Plan [Member]
Two thousand and twenty employee stock purchase plan.
Common stock issued in a public offering, net of offering expenses
Stock Issued During Period, Value, New Issues
Options under plan may be granted for periods
Share Based Compensation Options Under Plan May Be Granted For Periods
Share based compensation options under plan may be granted for periods.
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Restatement Determination Date:
Restatement Determination Date [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Computer equipment and software
Computer Equipment And Software [Member]
Computer equipment and software.
Title of 12(b) Security
Title of 12(b) Security
Common stock, $0.0001 par value; 300,000,000 shares authorized at December 31, 2024 and 2023; and 60,860,838 and 59,921,002 shares issued and outstanding at December 31, 2024 and December 31, 2023, respectively;
Common Stock, Value, Issued
Document Financial Statement Error Correction
Document Financial Statement Error Correction [Flag]
Share-based Payment Arrangement [Abstract]
Share-Based Payment Arrangement [Abstract]
General and administrative costs (excluding stock-based compensation)
General And Administrative Expense, Adjusted
General And Administrative Expense, Adjusted
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
State taxes, net of federal tax benefit
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member]
Schedule of Useful Lives of Property and Equipment
Property Plant And Equipment Useful Lives Table [Table Text Block]
Tabular disclosure of property plant and equipment useful lives.
Auditor Name
Auditor Name
Auditor Information [Abstract]
Auditor Information
Forfeited (USD per share)
Weighted-Average Grant Date fair value, forfeited (USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Cash flows from financing activities
Net Cash Provided by (Used in) Financing Activities [Abstract]
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member]
Preferred stock, $0.0001 par value 10,000,000 shares authorized at December 31, 2024 and 2023, none issued or outstanding at December 31, 2024 and 2023
Preferred Stock, Value, Issued
Prepayment fee percentage
Debt Instrument, Prepayment Fee Percentage
Debt Instrument, Prepayment Fee Percentage
Adjusted Cost
Debt Securities, Held-to-Maturity, Excluding Accrued Interest, before Allowance for Credit Loss
Property, plant and equipment, useful life
Property, Plant and Equipment, Useful Life
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Cash and Cash Equivalents
Cash and Cash Equivalents [Domain]
Total deferred tax liabilities
Deferred Tax Liabilities, Gross
Restricted stock awards
Restricted Common Stock Awards [Member]
Restricted common stock awards.
Percent of outstanding shares, shares added per year to plan
Percent Of Outstanding Shares, Shares Added Per Year To Plan
Percent Of Outstanding Shares, Shares Added Per Year To Plan
Basic (USD per share)
Earnings Per Share, Basic
Accounts payable
Increase (Decrease) in Accounts Payable
Cash paid for operating lease liabilities in operating cash flows
Operating Lease, Payments
Adjustment To PEO Compensation, Footnote
Adjustment To PEO Compensation, Footnote [Text Block]
Award Timing MNPI Disclosure
Award Timing MNPI Disclosure [Text Block]
Expiration period from date of grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Amortization (accretion) on short-term investments and debt
Accretion (Amortization) of Discounts And Premiums, Investments And Debt
Accretion (Amortization) of Discounts And Premiums, Investments And Debt
Other
Other Prepaid Expense, Current
Valuation allowance as a percentage on total deferred tax assets
Valuation Allowance As Percentage On Deferred Tax Assets
Valuation allowance as percentage on deferred tax assets.
Other
Deferred Tax Assets, Tax Deferred Expense, Other
Purchase of property and equipment in accounts payable
Capital Expenditures Incurred but Not yet Paid
Aggregate Pension Adjustments Service Cost
Aggregate Pension Adjustments Service Cost [Member]
Property and Equipment, Net
Property, Plant and Equipment, Policy [Policy Text Block]
Compensation Actually Paid vs. Other Measure
Compensation Actually Paid vs. Other Measure [Text Block]
Stock, Class of Stock [Table]
Stock, Class of Stock [Table]
Total current liabilities
Liabilities, Current
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member]
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Unrecognized compensation cost
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Total assets
Assets
2015 and 2020 Equity Incentive Plans and 2020 Inducement Plan
Two Thousand Fifteen And Two Thousand Twenty Equity Incentive Plans And Two Thousand Twenty Two Inducement Plan [Member]
Two Thousand Fifteen And Two Thousand Twenty Equity Incentive Plans And Two Thousand Twenty Two Inducement Plan
Concentration of Credit Risk and Other Risks and Uncertainties
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Line of credit
Long-Term Line of Credit
Granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Proceeds from issuances of common stock under benefit plans
Proceeds From Issuances Of Common Stock Under Benefit Plans
Proceeds From Issuances Of Common Stock Under Benefit Plans
Purchase of property and equipment
Payments to Acquire Property, Plant, and Equipment
Common stock shares outstanding percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Forgone Recovery due to Violation of Home Country Law, Amount
Forgone Recovery due to Violation of Home Country Law, Amount
Reconciliation of segment loss
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Abstract]
Commitments and Contingencies (Note 14)
Commitments and Contingencies
Stock-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Risk-free interest rate, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Schedule of Reconciliation of U.S. Federal Statutory Income Tax Rate to Company’s Effective Income Tax Rate
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Common stock fair market value percentage
Common Stock Fair Market Value Percentage
Common stock fair market value percentage .
Termination Date
Trading Arrangement Termination Date
Fixed asset basis
Deferred Tax Liabilities, Fixed Asset Basis
Deferred Tax Liabilities, Fixed Asset Basis
Expected volatility, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Organization and Description of Business
Business Description and Basis of Presentation [Text Block]
Related Party Transaction [Table]
Related Party Transaction [Table]
Revenues
Revenues
2026
Lessee, Operating Lease, Liability, to be Paid, Year Two
Stock-Based Compensation
Share-Based Payment Arrangement [Text Block]
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense [Abstract]
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense [Abstract]
Exercise price as a percentage of estimated grant date fair value of shares
Share Based Compensation Arrangement By Share Based Payment Award Exercise Price With Purchase Price Of Common Stock Percentage Of Estimated Grant Date Fair Value For Shareholders
Share based compensation arrangement by share based payment award exercise price with purchase price of common stock percentage of estimated grant date fair value for shareholders.
Entity Address, City or Town
Entity Address, City or Town
Deferred tax assets:
Deferred Tax Assets, Gross [Abstract]
Leases
Lessee, Leases [Policy Text Block]
Debt Instrument [Axis]
Debt Instrument [Axis]
Schedule of Option Activity Under the 2015 Plan and 2020 Plan
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Maturity of short-term investments
Proceeds from Maturities, Prepayments and Calls of Short-Term Investments
Intrinsic value of time-based stock options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Share-based payment arrangement, expense
Total stock-based compensation expense
Share-Based Payment Arrangement, Expense
Net loss
Net loss
Net loss
Net Income (Loss) Attributable to Parent
Trading Arrangement:
Trading Arrangement [Axis]
Unrecognized tax benefits, income tax penalties and interest expense
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Granted (USD per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Pay vs Performance Disclosure, Table
Pay vs Performance [Table Text Block]
Forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Debt Draw Period [Domain]
Debt Draw Period [Domain]
Debt Draw Period [Domain]
Equity Awards Adjustments, Excluding Value Reported in Compensation Table
Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member]
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member]
Entity File Number
Entity File Number
Right of use asset
Deferred Tax Liabilities, Leasing Arrangements
Cash and Cash Equivalents
Cash and Cash Equivalents [Axis]
Document Fiscal Year Focus
Document Fiscal Year Focus
Income Statement [Abstract]
Income Statement [Abstract]
Entity Address, Address Line One
Entity Address, Address Line One
Second Anniversary
Second Anniversary [Member]
Second Anniversary
Debt Instrument, Name [Domain]
Debt Instrument, Name [Domain]
Prepaid Expenses and Other Current Assets
Prepaid Expenses And Other Current Assets [Text Block]
Prepaid Expenses And Other Current Assets
Lease term
Lessee, Operating Lease, Term of Contract
Assets measured at fair value
Assets, Fair Value Disclosure
Name
Forgone Recovery, Individual Name
Aggregate intrinsic value, exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Weighted-average remaining lease term (in years)
Operating Lease, Weighted Average Remaining Lease Term
Document Period End Date
Document Period End Date
Sale of Stock [Axis]
Sale of Stock [Axis]
Short-Term Investments
Interest and other income (expense)
Investment, Policy [Policy Text Block]
Award Timing MNPI Considered
Award Timing MNPI Considered [Flag]
Total undiscounted lease payments
Total undiscounted lease payments
Lessee, Operating Lease, Liability, to be Paid
Outstanding and unvested, beginning balance (in shares)
Outstanding and unvested, ending balance (in shares)
Outstanding and unvested (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Line of Credit Facility, Lender [Domain]
Line of Credit Facility, Lender [Domain]
Insider Trading Arrangements [Line Items]
Adjusted Cost
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss
(Reductions) additions for tax positions of prior year
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Reportable Segment
Reportable Segment [Member]
Reportable Segment
Outstanding Aggregate Erroneous Compensation Amount
Outstanding Aggregate Erroneous Compensation Amount
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
2027
Lessee, Operating Lease, Liability, to be Paid, Year Three
PEO Actually Paid Compensation Amount
PEO Actually Paid Compensation Amount
Adjustment to Compensation:
Adjustment to Compensation [Axis]
Loan Agreement
Loan Agreement [Member]
Loan Agreement
Prepaid expenses and other current assets (Note 5)
Total prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Document Transition Report
Document Transition Report
Debt instrument final payment, percentage of original principal amount drawn
Debt Instrument Final Payment, Percentage Of Original Principal Amount Drawn
Debt Instrument Final Payment, Percentage Of Original Principal Amount Drawn
Schedule of Reconciliation of Unrecognized Tax Benefits
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Accumulated other comprehensive gain
Accumulated Other Comprehensive Income (Loss), Net of Tax
Entity Current Reporting Status
Entity Current Reporting Status
Accumulated Deficit
Retained Earnings [Member]
Proceeds from sale of common stock in a public offering
Proceeds from Issuance Initial Public Offering
Pension Adjustments Service Cost
Pension Adjustments Service Cost [Member]
Pliant Therapeutics
Pliant Therapeutics [Member]
Pliant Therapeutics
Contractual arrangements cancellation period
Contractual Arrangements Cancellation Period
Contractual arrangements cancellation period.
Related Party
Related and Nonrelated Parties [Axis]
Weighted average shares used in computing net loss per share - basic (in shares)
Weighted Average Number of Shares Outstanding, Basic
Stock Price or TSR Estimation Method
Stock Price or TSR Estimation Method [Text Block]
Decrease in right-of -use assets and liabilities from lease modifications
Decrease in Right-of -Use Assets and Liabilities from Lease Modifications
Decrease in Right-of -Use Assets and Liabilities from Lease Modifications
Restricted stock units
Restricted Stock Units (RSUs) [Member]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Executive Category:
Executive Category [Axis]
Capitalized research and development
Deferred Tax Assets, Capitalized Research And Development
Deferred Tax Assets, Capitalized Research And Development
Name
Awards Close in Time to MNPI Disclosures, Individual Name
Construction-in-progress
Construction in Progress [Member]
Forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Entity Filer Category
Entity Filer Category
Statement of Income Location, Balance
Statement of Income Location, Balance [Domain]
Letter of Credit
Letter of Credit [Member]
Schedule of Prepaid Expenses and Other Current Assets
Schedule Of Prepaid Expenses And Other Current Assets [Table Text Block]
Schedule Of Prepaid Expenses And Other Current Assets
Company Selected Measure Name
Company Selected Measure Name
Private Placement
Private Placement [Member]