0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 0000002 - Statement - Condensed Balance Sheets (Unaudited) link:presentationLink link:calculationLink link:definitionLink 0000003 - Statement - Condensed Balance Sheets (Unaudited) (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 0000004 - Statement - Condensed Statements of Operations and Comprehensive Loss (Unaudited) link:presentationLink link:calculationLink link:definitionLink 0000005 - Statement - Condensed Statements of Stockholders’ Equity (Unaudited) link:presentationLink link:calculationLink link:definitionLink 0000006 - Statement - Condensed Statements of Cash Flows (Unaudited) link:presentationLink link:calculationLink link:definitionLink 0000007 - Disclosure - Organization and Description of Business link:presentationLink link:calculationLink link:definitionLink 0000008 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 0000009 - Disclosure - Financial Instruments link:presentationLink link:calculationLink link:definitionLink 0000010 - Disclosure - Property and Equipment, net link:presentationLink link:calculationLink link:definitionLink 0000011 - Disclosure - Prepaid Expenses and Other Current Assets link:presentationLink link:calculationLink link:definitionLink 0000012 - Disclosure - Accrued Liabilities link:presentationLink link:calculationLink link:definitionLink 0000013 - Disclosure - Long-term Debt link:presentationLink link:calculationLink link:definitionLink 0000014 - Disclosure - Novartis Collaboration and License Agreement ("the Novartis Agreement") link:presentationLink link:calculationLink link:definitionLink 0000015 - Disclosure - Preferred Stock link:presentationLink link:calculationLink link:definitionLink 0000016 - Disclosure - Common Stock link:presentationLink link:calculationLink link:definitionLink 0000017 - Disclosure - Equity Incentive Plans and Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 0000018 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 0000019 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 0000020 - Disclosure - Defined Contribution Plan link:presentationLink link:calculationLink link:definitionLink 0000021 - Disclosure - Net Loss Per Share Attributable to Common Stockholders link:presentationLink link:calculationLink link:definitionLink 9954701 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9954702 - Disclosure - Financial Instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 9954703 - Disclosure - Property and Equipment, net (Tables) link:presentationLink link:calculationLink link:definitionLink 9954704 - Disclosure - Prepaid Expenses and Other Current Assets (Tables) link:presentationLink link:calculationLink link:definitionLink 9954705 - Disclosure - Accrued Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 9954706 - Disclosure - Long-term Debt (Tables) link:presentationLink link:calculationLink link:definitionLink 9954707 - Disclosure - Common Stock (Tables) link:presentationLink link:calculationLink link:definitionLink 9954708 - Disclosure - Equity Incentive Plans and Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9954709 - Disclosure - Net Loss Per Share Attributable to Common Stockholders (Tables) link:presentationLink link:calculationLink link:definitionLink 9954710 - Disclosure - Organization and Description of Business (Details) link:presentationLink link:calculationLink link:definitionLink 9954711 - Disclosure - Financial Instruments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954712 - Disclosure - Financial Instruments - Summary of Cash and Cash Equivalents, Money Market Funds and Short-term Investments by Significant Investment Category (Details) link:presentationLink link:calculationLink link:definitionLink 9954713 - Disclosure - Property and Equipment, net - Schedule of Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 9954714 - Disclosure - Property and Equipment, net - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954715 - Disclosure - Prepaid Expenses and Other Current Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9954716 - Disclosure - Accrued Liabilities - Summary of Accrued Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9954717 - Disclosure - Long-term Debt - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954718 - Disclosure - Long-term Debt - Schedule of Maturities of Long-Term Debt (Details) link:presentationLink link:calculationLink link:definitionLink 9954719 - Disclosure - Novartis Collaboration and License Agreement (the "Novartis Agreement") - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954720 - Disclosure - Preferred Stock (Details) link:presentationLink link:calculationLink link:definitionLink 9954721 - Disclosure - Common Stock - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954722 - Disclosure - Common Stock - Schedule of Shares Reserved for Future Issuance (Details) link:presentationLink link:calculationLink link:definitionLink 9954723 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Equity Incentive Plan - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954724 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Incentive Stock Options and Nonqualified Stock Options - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954725 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Summary of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for Stock Option Awards (Details) link:presentationLink link:calculationLink link:definitionLink 9954726 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Summary of Option Activity Under the 2015 Plan and 2020 Plan (Details) link:presentationLink link:calculationLink link:definitionLink 9954727 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Restricted Common Stock Awards - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954728 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Restricted Stock Units and Performance-Based Restricted Stock Units - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954729 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Summary of Restricted Stock Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9954730 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Schedule of TSR PSU Valuation Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 9954731 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - 2020 Employee Stock Purchase Plan - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9954732 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - 2020 Employee Stock Purchase Plan - Summary of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for 2020 Employee Stock Purchase Plan (Details) link:presentationLink link:calculationLink link:definitionLink 9954733 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Summary of Stock-based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9954734 - Disclosure - Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9954735 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 9954736 - Disclosure - Defined Contribution Plan (Details) link:presentationLink link:calculationLink link:definitionLink 9954737 - Disclosure - Net Loss Per Share Attributable to Common Stockholders - Summary of Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9954738 - Disclosure - Net Loss Per Share Attributable to Common Stockholders - Reconciliation of Numerator and Denominator Used in Calculation of Basic and Diluted Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink